- 文献引用 : 3
|Application ||WB, E|
|Calculated MW||10124 Da|
|Other Names||CG4494-PA; LD07775p; Smt3; Ubiquitin-like protein SMT3|
|Target/Specificity||This Drosophila SUMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the C-terminal region of human Drosophila SUMO.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||D SUMO Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Nucleus .|
Author : Maarifi G1, Hannoun Z1, Geoffroy MC1, El Asmi F1, Zarrouk K1, Nisole S1, Blondel D2, Chelbi-Alix MK3.
J Virol. 2016 May 11. pii: JVI.00722-16. [Epub ahead of print]
Author : Kearse MG, Ireland JA, Prem SM, Chen AS, Ware VC.
Nucleus. 2013 May-Jun;4(3):241-58. doi: 10.4161/nucl.25261. Epub 2013 Jun 6.
Author : Sahota VK, Grau BF, Mansilla A, FerrÃºs A.
J Cell Sci. 2009 Aug 1;122(Pt 15):2623-31. doi: 10.1242/jcs.050880. Epub 2009 Jun 30.
Provided below are standard protocols that you may find useful for product applications.
Covalent modification of target lysines by SUMO (small ubiquitin-like modifier) modulates processes such as protein localization, transcription, nuclear transport, mitosis, DNA replication and repair, signal transduction, and viral reproduction. SUMO does not seem to be involved in protein degradation and may in fact function as an antagonist of ubiquitin in the degradation process. In the development of Drosophila, SUMO plays a maternal role in anterior-posterior (A/P) polarity and patterning.
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