注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   其他   >   SNRPD3 Antibody (N-term)   

SNRPD3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
标注"皇冠"的产品,是满足高质量标准的产品。
了解更多...
  • 1 - SNRPD3 Antibody (N-term) AP12451a
    Anti-SNRPD3 Antibody (N-term) at 1:2000 dilution + COLO 205 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - SNRPD3 Antibody (N-term) AP12451a
    All lanes : Anti-SNRPD3 Antibody (N-term) at 1:4000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: 293 whole cell lysate Lane 4: Jurkat whole cell lysate Lane 5: HL-60 whole cell lysate Lane 6: Mouse heart tissue lysate Lane 7: NIH/3T3 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 14 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 产品详情
  • 文献引用 : 1
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P62318
Other Accession P62323, P62320, O44437, NP_004166.1
Reactivity Human, Mouse
Predicted Xenopus, Drosophila
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 6634
Other Names Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3, SNRPD3
Target/Specificity This SNRPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SNRPD3.
Dilution WB~~1:4000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRPD3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNRPD3
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes
Research Areas
A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models.
Author : Chan-Penebre E1, Kuplast KG1, Majer CR2, Boriack-Sjodin PA1, Wigle TJ2, Johnston LD1, Rioux N1, Munchhof MJ1, Jin L3, Jacques SL1, West KA1<
Nat Chem Biol. 2015 Apr 27. doi: 10.1038/nchembio.1810. [Epub ahead of print]
25915199

BACKGROUND

The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.

REFERENCES

Gonsalvez, G.B., et al. J. Cell Biol. 178(5):733-740(2007)
Ma, Y., et al. Structure 13(6):883-892(2005)
Mahler, M., et al. Arthritis Res. Ther. 7 (1), R19-R29 (2005) :
Ong, S.E., et al. Nat. Methods 1(2):119-126(2004)
Ong, S.E., et al. Nat. Methods 1(2):119-126(2004)

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价