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TBC1D3E Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TBC1D3E Antibody (C-term) AP12276b
    Anti-TBC1D3E Antibody (C-term) at 1:1000 dilution + NCI-H292 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession A6NER0
Other Accession P0C7X1, Q6DHY5, Q6IPX1, A6NDS4, NP_001116863.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62185 Da
Additional info
Gene ID 84218
Other Names TBC1 domain family member 3F, TBC1D3F, TBC1D3E
Target/Specificity This TBC1D3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 498-527 amino acids from the C-terminal region of human TBC1D3E.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTBC1D3E Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TBC1D3F
Synonyms TBC1D3E
Function Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).
Cellular Location Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.
Tissue Location Expressed in most tissues including pancreas, thymus and testis.
Research Areas

BACKGROUND

TBC1D3E acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity).

REFERENCES

Alkan, C., et al. Nat. Genet. 41(10):1061-1067(2009)
Wainszelbaum, M.J., et al. J. Biol. Chem. 283(19):13233-13242(2008)
Hodzic, D., et al. Genomics 88(6):731-736(2006)
Zody, M.C., et al. Nature 440(7087):1045-1049(2006)
Paulding, C.A., et al. Proc. Natl. Acad. Sci. U.S.A. 100(5):2507-2511(2003)

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