DUX4 Antibody (Center)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- 背景知识
Application ![]()
| FC, WB, E |
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Primary Accession | Q9UBX2 |
Other Accession | Q6RFH8, P0CJ90, P0CJ89, P0CJ88, P0CJ87, P0CJ86, P0CJ85 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit Ig |
Calculated MW | 44940 Da |
Gene ID | 100288687 |
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Other Names | Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800}, Double homeobox protein 10 {ECO:0000312|EMBL:AAK915091}, DUX4 (HGNC:50800), DUX10 |
Target/Specificity | This DUX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-275 amino acids from the Central region of human DUX4. |
Dilution | FC~~1:25 WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DUX4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DUX4 (HGNC:50800) |
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Synonyms | DUX10 |
Function | Involved in transcriptional regulation. May regulate microRNA (miRNA) expression. |
Cellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000269|PubMed:15709750, ECO:0000269|PubMed:21060811}. Note=Actively transported through the nuclear pore complex (NPC) |
Tissue Location | Does not seem to be expressed in normal muscle, but is detected in muscle of individuals with FSHD, and also in testis (at protein level) (PubMed:21060811). Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells |
Research Areas
BACKGROUND
DUX4 may be involved in transcriptional regulation.

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