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>   首页   >   产品   >   一抗   >   信号转导   >   Mouse MOGT2 Antibody (C-term)   

Mouse MOGT2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - Mouse MOGT2 Antibody (C-term) AP1122b
    Western blot analysis of lysate from mouse skeletal muscle tissue lysate, using MOGT2 Antibody (C-term)(Cat. #AP1122b). AP1122b was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q80W94
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38591 Da
Additional info
Gene ID 233549
Other Names 2-acylglycerol O-acyltransferase 2, Acyl-CoA:monoacylglycerol acyltransferase 2, MGAT2, Diacylglycerol acyltransferase 2-like protein 5, Monoacylglycerol O-acyltransferase 1-like, Monoacylglycerol O-acyltransferase 2, Mogat2, Dgat2l5, Mgat1l
Target/Specificity This Mouse MOGT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-312 amino acids from the C-terminal region of mouse MOGT2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse MOGT2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mogat2
Synonyms Dgat2l5, Mgat1l
Function Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Mainly expressed in small intestine. Detected in the small intestine in a proximal-to-distal gradient that correlated with fat absorption pattern. Present not only in the villi, but also in the crypt regions of the small intestine, which suggests that expression occurs prior to the maturation of enterocytes. Not detectable in other sections of the digestive tract, including stomach, cecum, colon and rectum, or other tissues such as kidney, liver and adipocytes (at protein level) Also detected in kidney, adipose and stomach. Expressed at very low level in liver, skeletal muscle and spleen. Not expressed in brain, heart, lung, skin, testis and thymus
Research Areas

BACKGROUND

MOGT2 catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. It exhibits a preference toward monoacylglycerols containing unsaturated fatty acids in the order of C18:3 > C18:2 > C18:1 > C18:0. This protein plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. MOGT2 may play a role in diet-induced obesity.

REFERENCES

Cao,J., J. Biol. Chem. 279 (18), 18878-18886 (2004)
Cao,J., J. Biol. Chem. 278 (28), 25657-25663 (2003)
Yen,C.L., J. Biol. Chem. 278 (20), 18532-18537 (2003)

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