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UNCX Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • 3 - UNCX Antibody (C-term) AP11164b
    Immunofluorescent analysis of U251 cells, using UNCX Antibody (C-term) (Cat. #AP11164b). AP11164b was diluted at 1:25 dilution. Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Dylight Fluor® 554 (red) conjugated Phalloidin (red).
  • 1 - UNCX Antibody (C-term) AP11164b
    UNCX Antibody (C-term) (Cat. #AP11164b) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the UNCX antibody detected the UNCX protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, E
Primary Accession A6NJT0
Other Accession NP_001073930.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53690 Da
Additional info
Gene ID 340260
Other Names Homeobox protein unc-4 homolog, Homeobox protein Uncx41, UNCX, UNCX41
Target/Specificity This UNCX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-410 amino acids from the C-terminal region of human UNCX.
Dilution IF~~1:25
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUNCX Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UNCX
Synonyms UNCX4.1
Function Transcription factor involved in somitogenesis and neurogenesis. Required for the maintenance and differentiation of particular elements of the axial skeleton. May act upstream of PAX9. Plays a role in controlling the development of connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}
Research Areas

BACKGROUND

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity).

REFERENCES

Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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