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>   首页   >   产品   >   一抗   >   细胞生物学   >   PMPCA Antibody (C-term)   

PMPCA Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - PMPCA Antibody (C-term) AP11161b
    PMPCA Antibody (C-term) (Cat. #AP11161b) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the PMPCA antibody detected the PMPCA protein (arrow).
  • 4 - PMPCA Antibody (C-term) AP11161b
    PMPCA Antibody (C-term) (Cat. #AP11161b) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q10713
Other Accession NP_055975.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58253 Da
Additional info
Gene ID 23203
Other Names Mitochondrial-processing peptidase subunit alpha, Alpha-MPP, P-55, PMPCA, INPP5E, KIAA0123, MPPA
Target/Specificity This PMPCA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-483 amino acids from the C-terminal region of human PMPCA.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPMPCA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PMPCA
Synonyms INPP5E, KIAA0123, MPPA
Function Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which is required for maturation of the majority of mitochondrial precursor proteins (PubMed:25808372). Most MPP cleavage sites follow an arginine at position -2 (By similarity).
Cellular Location Mitochondrion matrix {ECO:0000250|UniProtKB:P20069}. Mitochondrion inner membrane
Tissue Location Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.
Research Areas

REFERENCES

Hassel, S., et al. Proteomics 4(5):1346-1358(2004)
Harris, R.A., et al. Proteomics 2(2):212-223(2002)
Nagao, Y., et al. J. Biol. Chem. 275(44):34552-34556(2000)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Luciano, P., et al. J. Mol. Biol. 272(2):213-225(1997)

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