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>   首页   >   产品   >   一抗   >   细胞生物学   >   FBXO24 Antibody (Center)   

FBXO24 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - FBXO24 Antibody (Center) AP11008c
    FBXO24 Antibody (Center) (Cat. #AP11008c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FBXO24 antibody detected the FBXO24 protein (arrow).
  • 1 - FBXO24 Antibody (Center) AP11008c
    FBXO24 Antibody (Center) (Cat. #AP11008c) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the FBXO24 antibody detected the FBXO24 protein (arrow).
  • 14 - FBXO24 Antibody (Center) AP11008c
    FBXO24 antibody (Center) (Cat. #AP11008c) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXO24 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • 4 - FBXO24 Antibody (Center) AP11008c
    FBXO24 Antibody (Center) (Cat. #AP11008c) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, FC, E
Primary Accession O75426
Other Accession Q9D417, Q4R327, NP_001156971.1, NP_277041.1, NP_036304.2
Reactivity Human, Mouse
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64889 Da
Additional info
Gene ID 26261
Other Names F-box only protein 24, FBXO24, FBX24
Target/Specificity This FBXO24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human FBXO24.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXO24 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO24
Synonyms FBX24
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.
Research Areas

BACKGROUND

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

REFERENCES

Winston, J.T., et al. Curr. Biol. 9(20):1180-1182(1999)
Cenciarelli, C., et al. Curr. Biol. 9(20):1177-1179(1999)

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