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>   首页   >   产品   >   一抗   >   细胞生物学   >   LCE1A Antibody (C-term)   

LCE1A Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - LCE1A Antibody (C-term) AP10891b
    LCE1A Antibody (C-term) (Cat. #AP10891b) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the LCE1A antibody detected the LCE1A protein (arrow).
  • 14 - LCE1A Antibody (C-term) AP10891b
    LCE1A antibody (C-term) (Cat. #AP10891b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LCE1A antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q5T7P2
Other Accession NP_848125.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 353131
Other Names Late cornified envelope protein 1A, Late envelope protein 1, LCE1A, LEP1
Target/Specificity This LCE1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the C-terminal region of human LCE1A.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLCE1A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCE1A
Synonyms LEP1
Function Precursors of the cornified envelope of the stratum corneum.
Tissue Location Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
Research Areas

BACKGROUND

LCE1A belongs to the late cornified envelope (LCE) gene cluster within the epidermal differentiation complex (EDC) on chromosome 1. The LCE cluster contains multiple conserved genes that encode stratum corneum proteins, and these genes are expressed relatively late during fetal assembly of the skin cornified envelope (Jackson et al., 2005 [PubMed 15854049]). For further information on the LCE gene cluster, see GENE FAMILY below.

REFERENCES

Jackson, B., et al. J. Invest. Dermatol. 124(5):1062-1070(2005)
Marshall, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98(23):13031-13036(2001)

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