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>   首页   >   产品   >   一抗   >   细胞生物学   >   IMMP1L Antibody (C-term)   

IMMP1L Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - IMMP1L Antibody (C-term) AP10836B
    Anti-IMMP1L Antibody (C-term) at 1:1000 dilution + human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 19 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - IMMP1L Antibody (C-term) AP10836B
    IMMP1L Antibody (C-term) (Cat. #AP10836b) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the IMMP1L antibody detected the IMMP1L protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q96LU5
Other Accession Q9CQU8, NP_659418.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18504 Da
Additional info
Gene ID 196294
Other Names Mitochondrial inner membrane protease subunit 1, 3421-, IMP1-like protein, IMMP1L
Target/Specificity This IMMP1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-127 amino acids from the C-terminal region of human IMMP1L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIMMP1L Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IMMP1L
Function Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
Cellular Location Mitochondrion inner membrane
Research Areas

BACKGROUND

The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMP1 and IMP2 (IMMP2L; MIM 605977) are the catalytic subunits of the IMP complex (Burri et al., 2005 [PubMed 15814844]).

REFERENCES

Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Taylor, T.D., et al. Nature 440(7083):497-500(2006)
Burri, L., et al. Mol. Biol. Cell 16(6):2926-2933(2005)

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