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TAPT1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TAPT1 Antibody  (C-term) AP10831b
    TAPT1 Antibody (C-term) (Cat. #AP10831b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the TAPT1 antibody detected the TAPT1 protein (arrow).
  • 1 - TAPT1 Antibody  (C-term) AP10831b
    TAPT1 Antibody (C-term) (Cat. #AP10831b) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the TAPT1 antibody detected the TAPT1 protein (arrow).
  • 4 - TAPT1 Antibody  (C-term) AP10831b
    TAPT1 Antibody (C-term) (Cat. #AP10831b) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q6NXT6
Other Accession Q4VBD2, Q5ZLG8, NP_699196.2
Reactivity Human, Mouse
Predicted Chicken
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64260 Da
Additional info
Gene ID 202018
Other Names Transmembrane anterior posterior transformation protein 1 homolog, Cytomegalovirus partial fusion receptor, TAPT1, CMVFR
Target/Specificity This TAPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-558 amino acids from the C-terminal region of human TAPT1.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAPT1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAPT1
Synonyms CMVFR
Function May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169.
Cellular Location Membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

This gene encodes a highly conserved, putative transmembrane protein. A mutation in the mouse ortholog of this gene results in homeotic, posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants. This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development. An alternatively spliced transcript variant encoding a substantially different isoform has been described, but its biological validity has not been determined.

REFERENCES

Howell, G.R., et al. Genetics 175(2):699-707(2007)
Baldwin, B.R., et al. J. Gen. Virol. 81 (PT 1), 27-35 (2000) :
Baldwin, B.R., et al. Biochem. Biophys. Res. Commun. 219(2):668-673(1996)

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