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ORML2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ORML2 Antibody  (Center) AP10815c
    Western blot analysis of lysate from human heart tissue lysate, using ORML2 Antibody (Center)(Cat. #AP10815c). AP10815c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • 14 - ORML2 Antibody  (Center) AP10815c
    ORML2 Antibody (Center) (Cat. #AP10815c) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ORML2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession Q53FV1
Other Accession Q6QI25, Q9CPZ6, Q8N138, Q5XJR6, Q0VD15, Q9CQZ0, Q5E972, Q5XH57, Q9P0S3, Q8JFB7, Q29RQ9, NP_054901.1
Reactivity Human
Predicted Bovine, Zebrafish, Xenopus, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 17363 Da
Additional info
Gene ID 29095
Other Names ORM1-like protein 2, Adoplin-2, ORMDL2
Target/Specificity This ORML2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human ORML2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsORML2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ORMDL2
Function Negative regulator of sphingolipid synthesis.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus
Research Areas

BACKGROUND

Negative regulator of sphingolipid synthesis.

REFERENCES

Hjelmqvist, L., et al. Genome Biol. 3 (6), RESEARCH0027 (2002) :

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