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>   首页   >   产品   >   一抗   >   发育生物学   >   TLL1 Antibody (C-term)   

TLL1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 14 - TLL1 Antibody (C-term) AP10755b
    TLL1 antibody (C-term) (Cat. #AP10755b) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TLL1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • 1 - TLL1 Antibody (C-term) AP10755b
    TLL1 Antibody (C-term) (Cat. #AP10755b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the TLL1 antibody detected the TLL1 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
IHC-P, WB, E
Primary Accession O43897
Other Accession Q62381, NP_036596.3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 114709 Da
Additional info
Gene ID 7092
Other Names Tolloid-like protein 1, 3424-, TLL1, TLL
Target/Specificity This TLL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 874-901 amino acids from the C-terminal region of human TLL1.
Dilution IHC-P~~1:50~100
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTLL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLL1
Synonyms TLL
Function Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.
Cellular Location Secreted.
Research Areas

BACKGROUND

This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. A similar protein in mice is required during heart development and specifically processes procollagen C-propeptides and chordin at similar cleavage sites.

REFERENCES

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Berry, R., et al. FEBS Lett. 584(4):657-661(2010)
Sabirzhanova, I.B., et al. Biochem. Biophys. Res. Commun. 389(2):338-342(2009)
Stanczak, P., et al. Eur. J. Hum. Genet. 17(3):344-351(2009)
Mac Sweeney, A., et al. J. Mol. Biol. 384(1):228-239(2008)

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