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SERPINA6 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - SERPINA6 Antibody (Center) AP10736c
    Western blot analysis of lysate from human blood plasma tissue lysate, using SERPINA6 Antibody (Center)(Cat. #AP10736c). AP10736c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
  • 3 - SERPINA6 Antibody (Center) AP10736c
    Confocal immunofluorescent analysis of SERPINA6 Antibody (Center) (Cat#AP10736c) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IF, E
Primary Accession P08185
Other Accession NP_001747.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45141 Da
Additional info
Gene ID 866
Other Names Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG
Target/Specificity This SERPINA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the Central region of human SERPINA6.
Dilution WB~~1:1000
IF~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINA6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINA6
Synonyms CBG
Function Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
Cellular Location Secreted.
Tissue Location Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells
Research Areas

BACKGROUND

This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.

REFERENCES

Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Holliday, K.L., et al. J Psychosom Res 68(5):469-474(2010)
Braun, B.C., et al. J. Steroid Biochem. Mol. Biol. 120(1):30-37(2010)
Lewis, J.G., et al. Horm. Metab. Res. 42(4):274-279(2010)

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