|Application ||WB, FC, E|
|Calculated MW||42310 Da|
|Other Names||N-acetyllactosaminide beta-1, 3-N-acetylglucosaminyltransferase 4, UDP-GlcNAc:betaGal beta-1, 3-N-acetylglucosaminyltransferase 4, BGnT-4, Beta-1, 3-Gn-T4, Beta-1, 3-N-acetylglucosaminyltransferase 4, Beta3Gn-T4, B3GNT4|
|Target/Specificity||This B3GNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-260 amino acids from the Central region of human B3GNT4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||B3GNT4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Mainly expressed in brain tissues such as whole brain, hippocampus, amygdala, cerebellum and caudate nucleus. Also expressed in colon, esophagus and kidney|
Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase protein family. The encoded enzyme is involved in the biosynthesis of poly-N-acetyllactosamine chains and prefers lacto-N-neotetraose as a substrate. It is a type II transmembrane protein. [provided by RefSeq].
Shiraishi, N., et al. J. Biol. Chem. 276(5):3498-3507(2001)
Amado, M., et al. Biochim. Biophys. Acta 1473(1):35-53(1999)