注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   心血管   >   APCS Antibody (C-term)   

APCS Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - APCS Antibody (C-term) AP10677b
    APCS Antibody (C-term) (Cat. #AP10677b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the APCS antibody detected the APCS protein (arrow).
  • 14 - APCS Antibody (C-term) AP10677b
    APCS antibody (C-term) (Cat. #AP10677b) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the APCS antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, IHC-P, E
Primary Accession P02743
Other Accession Q13449, NP_001630.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25387 Da
Additional info
Gene ID 325
Other Names Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2
Target/Specificity This APCS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-178 amino acids from the C-terminal region of human APCS.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAPCS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APCS
Synonyms PTX2
Function Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Cellular Location Secreted.
Tissue Location Found in serum and urine.
Research Areas

BACKGROUND

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

REFERENCES

Song, Z., et al. Atherosclerosis 211(1):90-95(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Lu, J., et al. Nature 456(7224):989-992(2008)
Verwey, N.A., et al. Dement Geriatr Cogn Disord 26(6):522-527(2008)

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价