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>   首页   >   产品   >   一抗   >   免疫学   >   TIGIT Antibody (C-term)   

TIGIT Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - TIGIT Antibody (C-term) AP10616b
    TIGIT Antibody (C-term) (Cat. #AP10616b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).
  • 1 - TIGIT Antibody (C-term) AP10616b
    TIGIT Antibody (C-term) (Cat. #AP10616b) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TIGIT antibody detected the TIGIT protein (arrow).
  • 4 - TIGIT Antibody (C-term) AP10616b
    TIGIT Antibody (C-term) (Cat. #AP10616b) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q495A1
Other Accession NP_776160.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 201633
Other Names T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, TIGIT, VSIG9, VSTM3
Target/Specificity This TIGIT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-233 amino acids from the C-terminal region of human TIGIT.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTIGIT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIGIT
Synonyms VSIG9, VSTM3
Function Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level)
Research Areas

BACKGROUND

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.

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