注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   癌症   >   CASC4 Antibody (C-term)   

CASC4 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - CASC4 Antibody  (C-term) AP10511b
    CASC4 Antibody (C-term) (Cat. #AP10511b) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the CASC4 antibody detected the CASC4 protein (arrow).
  • 4 - CASC4 Antibody  (C-term) AP10511b
    CASC4 Antibody (C-term) (Cat. #AP10511b) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q6P4E1
Other Accession Q6P2L7, NP_816929.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48864 Da
Additional info
Gene ID 113201
Other Names Protein CASC4, Cancer susceptibility candidate gene 4 protein, CASC4
Target/Specificity This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCASC4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CASC4
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas

BACKGROUND

The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30% of human breast and 20% of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

REFERENCES

Lamesch, P., et al. Genomics 89(3):307-315(2007)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Sato, T., et al. Onkologie 26(3):268-271(2003)
Scheer, M., et al. Mund Kiefer Gesichtschir 7(3):138-145(2003)
Oh, J.J., et al. Nucleic Acids Res. 27(20):4008-4017(1999)

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价