|Application ||FC, WB, E|
|Other Accession||Q2IBD0, Q09YN2, Q2QLD7, Q99M96, Q2PG42, Q1RLU8, A0M8U1, A4D7R9, NP_060882.2|
|Predicted||Bovine, Chicken, Zebrafish, Monkey, Mouse, Pig, Rabbit, Rat|
|Calculated MW||67166 Da|
|Other Names||Suppressor of tumorigenicity 7 protein, Protein FAM4A1, Protein HELG, ST7, FAM4A1, HELG, RAY1|
|Target/Specificity||This ST7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human ST7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ST7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||FAM4A1, HELG, RAY1|
|Function||May act as a tumor suppressor.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitously expressed, with highest levels in heart, liver and pancreas.|
Provided below are standard protocols that you may find useful for product applications.
The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described.
Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009) de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)