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ST7 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ST7 Antibody (Center) AP10493c
    Anti-ST7 Antibody (Center) at 1:8000 dilution + Rat lung lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 4 - ST7 Antibody (Center) AP10493c
    ST7 Antibody (Center) (Cat. #AP10493c) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q9NRC1
Other Accession Q2IBD0, Q09YN2, Q2QLD7, Q99M96, Q2PG42, Q1RLU8, A0M8U1, A4D7R9, NP_060882.2
Reactivity Rat
Predicted Bovine, Chicken, Zebrafish, Monkey, Mouse, Pig, Rabbit, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 67166 Da
Additional info
Gene ID 7982
Other Names Suppressor of tumorigenicity 7 protein, Protein FAM4A1, Protein HELG, ST7, FAM4A1, HELG, RAY1
Target/Specificity This ST7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human ST7.
Dilution WB~~1:8000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsST7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ST7
Synonyms FAM4A1, HELG, RAY1
Function May act as a tumor suppressor.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed, with highest levels in heart, liver and pancreas.
Research Areas

BACKGROUND

The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described.

REFERENCES

Bailey, S.D., et al. Diabetes Care (2010) In press : Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009) de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)

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