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PAX1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 4 - PAX1 Antibody (C-term) AP10458b
    PAX1 Antibody (C-term) (Cat. #AP10458b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • 1 - PAX1 Antibody (C-term) AP10458b
    PAX1 Antibody (C-term) (Cat. #AP10458b) western blot analysis in HepG2,MDA-MB453,293,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the PAX1 antibody detected the PAX1 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
FC, WB, E
Primary Accession P15863
Other Accession NP_006183.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55499 Da
Additional info
Gene ID 5075
Other Names Paired box protein Pax-1, HuP48, PAX1, HUP48
Target/Specificity This PAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human PAX1.
Dilution FC~~1:10~50
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAX1
Synonyms HUP48
Function This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity).
Cellular Location Nucleus.
Research Areas

BACKGROUND

The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates (McGaughran et al., 2003 [PubMed 12774041]). See PAX7 (MIM 167410) for a discussion of paired box domain genes.

REFERENCES

Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)
Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)
Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)

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