|Application ||FC, WB, E|
|Calculated MW||55499 Da|
|Other Names||Paired box protein Pax-1, HuP48, PAX1, HUP48|
|Target/Specificity||This PAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 443-471 amino acids from the C-terminal region of human PAX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PAX1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column (By similarity).|
Provided below are standard protocols that you may find useful for product applications.
The PAX genes, including PAX1, are a highly conserved family of developmental control genes that encode transcription factors and have been shown to play a role in pattern formation during embryogenesis in vertebrates (McGaughran et al., 2003 [PubMed 12774041]). See PAX7 (MIM 167410) for a discussion of paired box domain genes.
Huang, T.H., et al. Int. J. Gynecol. Cancer 20(4):513-519(2010)
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Hillmer, A.M., et al. Nat. Genet. 40(11):1279-1281(2008)
Richards, J.B., et al. Nat. Genet. 40(11):1282-1284(2008)
Fei, Q., et al. Zhonghua Yi Xue Za Zhi 88(37):2597-2602(2008)