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>   首页   >   产品   >   一抗   >   癌症   >   ITGA11 Antibody (N-term)   

ITGA11 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • 1 - ITGA11 Antibody (N-term) AP10393a
    ITGA11 Antibody (N-term) (Cat. #AP10393a) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the ITGA11 antibody detected the ITGA11 protein (arrow).
  • 1 - ITGA11 Antibody (N-term) AP10393a
    ITGA11 Antibody (N-term) (Cat. #AP10393a) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the ITGA11 antibody detected the ITGA11 protein (arrow).
  • 4 - ITGA11 Antibody (N-term) AP10393a
    ITGA11 Antibody (N-term) (Cat. #AP10393a) flow cytometric analysis of Neuro-2a cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, FC, E
Primary Accession Q9UKX5
Other Accession P61622, NP_001004439.1
Reactivity Human, Mouse, Hamster
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Additional info
Gene ID 22801
Other Names Integrin alpha-11, ITGA11
Target/Specificity This ITGA11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the N-terminal region of human ITGA11.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITGA11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITGA11
Function Integrin alpha-11/beta-1 is a receptor for collagen.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location According to PubMed:10464311, highest levels of expression in uterus and heart, intermediate levels in skeletal muscle and intermediate to low levels in pancreas, kidney and placenta. According to PubMed:10486209, also found in brain, colon, lung, small intestine, stomach, testis, salivary glands, thyroid glands and prostate. Very low levels in peripheral blood lymphocytes, fetal brain and fetal liver
Research Areas

BACKGROUND

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein contains an I domain, is expressed in muscle tissue, dimerizes with beta 1 integrin in vitro, and appears to bind collagen in this form. Therefore, the protein may be involved in attaching muscle tissue to the extracellular matrix. Alternative transcriptional splice variants have been found for this gene, but their biological validity is not determined.

REFERENCES

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Lu, N., et al. Matrix Biol. 29(3):166-176(2010) Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009) Young, R.P., et al. Postgrad Med J 85(1008):515-524(2009) Barczyk, M.M., et al. J. Dent. Res. 88(7):621-626(2009)

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