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ADCYAP1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - ADCYAP1 Antibody AM8670b
    Anti-ADCYAP1 Antibody at 1:8000 dilution + ADCYAP1 recombinant protein Lysates/proteins at 20ng per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 18 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P18509
Reactivity Human
Predicted Human
Host Mouse
Clonality monoclonal
Isotype IgG1,κ
Clone Names 1996CT329.45.62
Calculated MW 18835 Da
Additional info
Gene ID 116
Other Names Pituitary adenylate cyclase-activating polypeptide, PACAP, PACAP-related peptide, PRP-48, Pituitary adenylate cyclase-activating polypeptide 27, PACAP-27, PACAP27, Pituitary adenylate cyclase-activating polypeptide 38, PACAP-38, PACAP38, ADCYAP1
Target/Specificity This ADCYAP1 antibody is generated from a mouse immunized with a recombinant protein from the human region of human ADCYAP1.
Dilution WB~~1:8000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADCYAP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADCYAP1
Function Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway. In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).
Cellular Location Secreted.
Research Areas

BACKGROUND

Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells. Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway.

REFERENCES

Ohkubo S.,et al.DNA Cell Biol. 11:21-30(1992).
Hosoya M.,et al.Biochim. Biophys. Acta 1129:199-206(1992).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kimura C.,et al.Biochem. Biophys. Res. Commun. 166:81-89(1990).
Emery A.C.,et al.Sci. Signal. 6:RA51-RA51(2013).

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