|Application ||WB, E|
|Calculated MW||42874 Da|
|Other Names||C-C chemokine receptor type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr virus-induced G-protein coupled receptor 1, EBI1, EBV-induced G-protein coupled receptor 1, MIP-3 beta receptor, CD197, CCR7, CMKBR7, EBI1, EVI1|
|Target/Specificity||This CCR7 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from the N-terminal region of human CCR7.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCR7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CMKBR7, EBI1, EVI1|
|Function||Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7|
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions.
Birkenbach M.P.,et al.J. Virol. 67:2209-2220(1993).
Schweickart V.L.,et al.Genomics 23:643-650(1994).
Kopatz S.A.,et al.Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.