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PSMC2 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • 1 - PSMC2 Antibody AM8659b
    All lanes : Anti-PSMC2 at 1:2000 dilution Lane 1: Jurkat whole cell lysate Lane 2: U-2OS whole cell lysate Lane 3: Hela whole cell lysate Lane 4: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P35998
Other Accession Q5E9F9, Q4R4R0, P46471
Reactivity Human
Predicted Bovine, Mouse
Host Mouse
Clonality monoclonal
Isotype IgG1,k
Clone Names 1851CT193.4.40
Calculated MW 48634 Da
Additional info
Gene ID 5701
Other Names 26S protease regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2, Protein MSS1, PSMC2, MSS1
Target/Specificity This antibody is generated from a mouse immunized with a recombinant protein from human.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSMC2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMC2
Synonyms MSS1
Function The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.
Cellular Location Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Colocalizes with TRIM5 in the cytoplasmic bodies.
Research Areas

BACKGROUND

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation.

REFERENCES

Shibuya H.,et al.Nature 357:700-702(1992).
Ohira M.,et al.Cancer Lett. 197:63-68(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).

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