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SYP Antibody (C-term)

Purified Mouse Monoclonal Antibody (Mab)

     
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  • 1 - SYP   Antibody (C-term) AM8625b
    All lanes : Anti-SYP Antibody (C-term) at 1:4000 dilution Lane 1: Human brain lysate Lane 2: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P08247
Other Accession Q62277, P07825, Q5YJC1
Reactivity Human, Mouse
Predicted Mouse, Rat
Host Mouse
Clonality monoclonal
Isotype IgG1,k
Clone Names 701CT23.9.8
Calculated MW 33845 Da
Additional info
Gene ID 6855
Other Names Synaptophysin, Major synaptic vesicle protein p38, SYP
Target/Specificity This SYP antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 220-253 amino acids from the C-terminal region of human SYP.
Dilution WB~~1:4000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSYP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYP
Function Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
Cellular Location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome
Tissue Location Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype
Research Areas

BACKGROUND

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

REFERENCES

Suedhof T.C.,et al.Nucleic Acids Res. 15:9607-9607(1987).
Oezcelik T.,et al.Am. J. Hum. Genet. 47:551-561(1990).
Fisher S.E.,et al.Genomics 45:340-347(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ross M.T.,et al.Nature 434:325-337(2005).

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