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WBP2 Antibody (C-term)

Purified Mouse Monoclonal Antibody (Mab)

     
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  • 1 - WBP2 Antibody (C-term) AM8599b
    All lanes : Anti-WBP2 Antibody (C-term) at 1:2000 dilution Lane 1: mouse heart lysate Lane 2: A549 whole cell lysate Lane 3: HL-60 whole cell lysate Lane 4: 293 whole cell lysate Lane 5: A2058 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28/32 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q969T9
Reactivity Human, Mouse
Host Mouse
Clonality monoclonal
Isotype IgG1
Clone Names 932CT1.3.7
Calculated MW 28087 Da
Additional info
Gene ID 23558
Other Names WW domain-binding protein 2, WBP-2, WBP2
Target/Specificity This WBP2 antibody is generated from a mouse immunized with a recombinant protein between 1-261 amino acids from the C-terminal region of human WBP2.
Dilution WB~~1:2000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWBP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WBP2
Function Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation (PubMed:16772533). In presence of estrogen, binds to ESR1- responsive promoters (PubMed:16772533). Required for YAP1 coactivation function on PGR activity (PubMed:16772533). Synergizes with WBP2 in enhancing PGR activity (PubMed:16772533). Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (By similarity).
Cellular Location Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated
Tissue Location Ubiquitous.
Research Areas

REFERENCES

Chen H.I.,et al.J. Biol. Chem. 272:17070-17077(1997).
Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616(1997).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).

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