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DCLK1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • 1 - DCLK1 Antibody AM8593b
    All lanes : Anti-DCLK1 Antibody at 1:4000 dilution Lane 1: human brain lysate Lane 2: mouse brain lysate Lane 3: TT whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 82 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession O15075
Reactivity Human, Mouse
Host Mouse
Clonality monoclonal
Isotype IgG1,k
Clone Names 1751CT665.1.72
Calculated MW 82224 Da
Additional info
Gene ID 9201
Other Names Serine/threonine-protein kinase DCLK1, 2.7.11.1, Doublecortin domain-containing protein 3A, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1, DCLK1, DCAMKL1, DCDC3A, KIAA0369
Target/Specificity This DCLK1 antibody is generated from a mouse immunized with a recombinant protein of human DCLK1.
Dilution WB~~1:4000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDCLK1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DCLK1
Synonyms DCAMKL1, DCDC3A, KIAA0369
Function Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
Tissue Location In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain.
Research Areas

BACKGROUND

Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.

REFERENCES

Omori Y.,et al.J. Hum. Genet. 43:169-177(1998).
Sossey-Alaoui K.,et al.Genomics 56:121-126(1999).
Nagase T.,et al.DNA Res. 4:141-150(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).

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