|Application ||WB, E|
|Calculated MW||23659 Da|
|Other Names||Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FNDC5, FRCP2|
|Target/Specificity||This FNDC5 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 12-152 amino acids from human FNDC5.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FNDC5 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Peroxisome membrane; Single-pass type I membrane protein. Note=Imported in peroxisomes through the PEX5 receptor pathway.|
|Tissue Location||Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen|
Irisin: Contrary to mouse, may not be involved in the beneficial effects of muscular exercise, nor in the induction of browning of human white adipose tissue.
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