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>   首页   >   产品   >   一抗   >   癌症   >   SERPINB3 Antibody   

SERPINB3 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - SERPINB3 Antibody AM8571b
    All lanes : Anti-SERPINB3 at 1:4000 dilution Lane 1: A431 whole cell lysate Lane 2: NCI-H292 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 45 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P29508
Reactivity Human
Host Mouse
Clonality monoclonal
Isotype IgG2b,k
Clone Names 798CT5.2.2
Calculated MW 44565 Da
Additional info
Gene ID 6317
Other Names Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1, SERPINB3, SCCA, SCCA1
Target/Specificity This antibody is generated from a mouse immunized with a recombinant between 1-390 amino acids from human.
Dilution WB~~1:4000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINB3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SERPINB3
Synonyms SCCA, SCCA1
Function May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
Cellular Location Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level
Tissue Location Squamous cells. Expressed in some hepatocellular carcinoma (at protein level)
Research Areas

BACKGROUND

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

REFERENCES

Suminami Y.,et al.Biochem. Biophys. Res. Commun. 181:51-58(1991).
Schneider S.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:3147-3151(1995).
Suminami Y.,et al.Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
Moore P.L.,et al.J. Biol. Chem. 278:46709-46717(2003).
Tong C.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.

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