注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   癌症   >   RAB20 Antibody   

RAB20 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • 1 - RAB20 Antibody AM8559b
    All lanes : Anti-RAB20 Antibody at 1:2000-1:4000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 26 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q9NX57
Reactivity Human
Host Mouse
Clonality monoclonal
Isotype IgG2a
Clone Names 1694CT210.142.16
Calculated MW 26277 Da
Additional info
Gene ID 55647
Other Names Ras-related protein Rab-20, RAB20
Target/Specificity This RAB20 antibody is generated from a mouse immunized with recombinant protein from human RAB20.
Dilution WB~~1:2000-1:4000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRAB20 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RAB20
Function Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
Cellular Location Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side Note=Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity) Recruited to phagosomes containing S.aureus or M.tuberculosis
Tissue Location Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
Research Areas

BACKGROUND

Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.

REFERENCES

Amillet J.-M.,et al.Hum. Pathol. 37:256-263(2006).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Seto S.,et al.Traffic 12:407-420(2011).

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价