|Application ||WB, FC, E|
|Calculated MW||83166 Da|
|Other Names||Glycine--tRNA ligase, 22.214.171.124, Diadenosine tetraphosphate synthetase, AP-4-A synthetase, Glycyl-tRNA synthetase, GlyRS, GARS|
|Target/Specificity||This GARS antibody is generated from a mouse immunized with a recombinant protein between 35-305 amino acids from human GARS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GARS Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.|
|Cellular Location||Cytoplasm. Mitochondrion|
|Tissue Location||Widely expressed, including brain and spinal cord.|
Catalyzes the attachment of glycine to tRNA(Gly). Is also able produce diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.
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