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>   首页   >   产品   >   一抗   >   癌症   >   Ntrk3 Antibody   

Ntrk3 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
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  • 1 - Ntrk3 Antibody AM8448b
    Western blot analysis of lysates from mouse brain, rat brain tissue lysate (from left to right), using Ntrk3 Antibody(Cat. #AM8448b). AM8448b was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 20μg per lane.
  • 1 - Ntrk3 Antibody AM8448b
    Western blot analysis of lysate from human brain tissue lysate, using Ntrk3 Antibody(Cat. #AM8448b). AM8448b was diluted at 1:1000. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysate at 20μg.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q6VNS1
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1,k
Clone Names 1454CT394.87.35
Calculated MW 92760 Da
Additional info
Gene ID 18213
Other Names NT-3 growth factor receptor, GP145-TrkC, Trk-C, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase, Ntrk3, TrkC
Target/Specificity This Ntrk3 antibody is generated from a mouse immunized with a recombinant protein of human Ntrk3.
Dilution WB~~1:1000
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNtrk3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ntrk3
Synonyms TrkC
Function Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Isoform 2 expression is restricted to specific areas in adult brain. Isoform 3 transcripts are readily detected early during embryogenesis and are expressed predominantly in adult brain and gonads.
Research Areas

BACKGROUND

Receptor for neurotrophin-3 (NT-3). This is a tyrosine- protein kinase receptor. Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1 (By similarity).

REFERENCES

Yamauchi J.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:14421-14426(2003).
Menn B.,et al.J. Comp. Neurol. 401:47-64(1998).
Ballif B.A.,et al.J. Proteome Res. 7:311-318(2008).

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