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>   首页   >   产品   >   一抗   >   精选抗体   >   G蛋白偶联受体抗体(GPCR)   >   DRD2 Antibody (C-term) (Ascites)   

DRD2 Antibody (C-term) (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - DRD2 Antibody (C-term) (Ascites) AM2152a
    DRD2 Antibody (C-term)(Ascites)(Cat. #AM2152a) western blot analysis in mouse brain tissue lysates (35μg/lane).This demonstrates the DRD2 antibody detected the DRD2 protein (arrow).
  • 1 - DRD2 Antibody (C-term) (Ascites) AM2152a
    DRD2 Antibody (C-term)(Ascites) (Cat. #AM2152a) western blot analysis in rat brain tissue lysates (35μg/lane).This demonstrates the DRD2 antibody detected the DRD2 protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P14416
Other Accession NP_057658.2
Reactivity Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 629CT62.2.2
Calculated MW 50619 Da
Additional info
Gene ID 1813
Other Names D(2) dopamine receptor, Dopamine D2 receptor, DRD2
Target/Specificity This DRD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the C-terminal region of human DRD2.
Dilution WB~~1:200~800
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRD2 Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRD2
Function Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas

BACKGROUND

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.

REFERENCES

Verma, V., et al. J. Biol. Chem. 285(45):35092-35103(2010)
Borroto-Escuela, D.O., et al. Biochem. Biophys. Res. Commun. 401(4):605-610(2010)
Stelzel, C., et al. J. Neurosci. 30(42):14205-14212(2010)
Huang, H.Y., et al. J. Formos. Med. Assoc. 109(10):736-739(2010)
Itokawa, M., et al. J. Pharmacol. Sci. 114(1):1-5(2010)

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