注册 | 登录
所有产品
  • 所有产品
  • 一抗
  • 裂解液
>   首页   >   产品   >   一抗   >   癌症   >   TNFRSF8/CD30 Antibody (Center) (Ascites)   

TNFRSF8/CD30 Antibody (Center) (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - TNFRSF8/CD30 Antibody (Center) (Ascites) AM2099a
    TNFRSF8/CD30 Antibody (Center)(Ascites)(Cat. #AM2099a) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the TNFRSF8/CD30 antibody detected the TNFRSF8/CD30 protein (arrow).
  • 产品详情
  • 实验流程
  • 背景知识
Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P28908
Other Accession NP_001234.2
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 595CT15.5.1
Calculated MW 63747 Da
Additional info
Gene ID 943
Other Names Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
Target/Specificity This TNFRSF8/CD30 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 294-321 amino acids from the Central region of human TNFRSF8/CD30.
Dilution WB~~1:100~1000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNFRSF8/CD30 Antibody (Center) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF8
Synonyms CD30, D1S166E
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas

BACKGROUND

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

REFERENCES

de Kleer, I., et al. J. Immunol. 185(4):2071-2079(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Halim, M.A., et al. Transplant. Proc. 42(3):801-803(2010)
Dong, L., et al. J. Biomed. Biotechnol. 2010, 569053 (2010) :
Kamali, K., et al. Exp Clin Transplant 7(4):237-240(2009)

FeedBack

终于等到您。感谢您使用ABGENT(百奇生物)抗体产品。
点击下方“我要评价 ”按钮提交您的反馈信息,您的反馈和评价是我们最宝贵的财富之一,
我们将在1-3个工作日内处理您的反馈信息。

如有疑问,联系:0512-69552906 tech.abgent@wuxiapptec.com.


我要评价