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STRA8 Antibody

Mouse Monoclonal Antibody (Mab)

     
  • 1 - STRA8 Antibody AM2091a
    Anti-STRA8 Antibody at 1:2000 dilution + Hela whole cell lysate Secondary Goat Anti-mouse IgM, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36908 Da Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - STRA8 Antibody AM2091a
    Anti-STRA8 Antibody at 1:8000 dilution + mouse bladder lysate Secondary Goat Anti-mouse IgM, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 36908 Da Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q7Z7C7
Other Accession NP_872295.1
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 526CT11.1.5
Additional info
Gene ID 346673
Other Names Stimulated by retinoic acid gene 8 protein homolog, STRA8 {ECO:0000312|EMBL:AAP471631}
Target/Specificity This STRA8 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 31-59 amino acids from human STRA8.
Dilution WB~~ 1:8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSTRA8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name STRA8 {ECO:0000312|EMBL:AAP47163.1}
Function Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:P70278}.
Tissue Location Expressed specifically in testis.
Research Areas

BACKGROUND

This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.

REFERENCES

Le Bouffant, R., et al. Hum. Reprod. 25(10):2579-2590(2010)
Aston, K.I., et al. Hum. Reprod. 25(6):1383-1397(2010)
Chen, B., et al. Asian J. Androl. 11(5):557-565(2009)
Houmard, B., et al. Biol. Reprod. 81(2):438-443(2009)
Stouffs, K., et al. Verh. K. Acad. Geneeskd. Belg. 71(3):115-139(2009)

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