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>   首页   >   产品   >   一抗   >   癌症   >   CALCA/CT Antibody   

CALCA/CT Antibody

Mouse Monoclonal Antibody (Mab)

     
  • 1 - CALCA/CT Antibody AM2021b
    CALCA/CT Antibody (Cat. #AM2021b) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the CALCA/CT antibody detected the CALCA/CT protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P01258
Other Accession NP_001732.1, NP_001029124.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgM
Clone Names 406CT21.4.3
Calculated MW 15466 Da
Additional info
Gene ID 796
Other Names Calcitonin, Calcitonin, Katacalcin, Calcitonin carboxyl-terminal peptide, CCP, PDN-21, CALCA, CALC1
Target/Specificity This CALCA/CT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-84 amino acids from human CALCA/CT.
Dilution WB~~1:100~250
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCALCA/CT Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CALCA
Synonyms CALC1
Function Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Cellular Location Secreted.
Research Areas

BACKGROUND

This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

REFERENCES

Giroux, S., et al. Bone 47(5):975-981(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Lee, J.Y., et al. Korean J Lab Med 30(4):406-413(2010)
Giovanella, L., et al. Clin. Chem. Lab. Med. 48(8):1163-1165(2010)
Hatzistilianou, M. ScientificWorldJournal 10, 1941-1946 (2010) :

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