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>   首页   >   产品   >   一抗   >   干细胞   >   IHH Antibody (C-term) (Ascites)   

IHH Antibody (C-term) (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - IHH Antibody (C-term) (Ascites) AM1981a
    IHH antibody (C-term) (Cat. #AM1981a) western blot analysis in CEM cell line lysates (35μg/lane).This demonstrates the IHH antibody detected the IHH protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q14623
Other Accession O75473, F1MT22, NP_034674.1
Reactivity Human
Predicted Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG3
Clone Names 363CT4.1.6
Calculated MW 45251 Da
Additional info
Gene ID 3549
Other Names Indian hedgehog protein, IHH, HHG-2, Indian hedgehog protein N-product, Indian hedgehog protein C-product, IHH
Target/Specificity This IHH Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human IHH.
Dilution WB~~1:500~8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIHH Antibody (C-term) (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IHH
Function Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP) (By similarity).
Cellular Location Indian hedgehog protein N-product: Cell membrane; Lipid-anchor; Extracellular side. Note=The N-terminal peptide remains associated with the cell surface. Cell membrane.
Tissue Location Expressed in embryonic lung, and in adult kidney and liver
Research Areas

BACKGROUND

Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).

REFERENCES

van Dop, W.A., et al. Gastroenterology 139(5):1665-1676(2010) Koike, S., et al. Biochem. Biophys. Res. Commun. 400(1):66-71(2010) Rice, D.P., et al. Hum. Mol. Genet. 19(17):3457-3467(2010) Witte, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14211-14216(2010) Lyashenko, N., et al. Dev. Dyn. 239(8):2266-2277(2010)

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