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>   首页   >   产品   >   一抗   >   心血管   >   APCS Antibody (Ascites)   

APCS Antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - APCS Antibody (Ascites) AM1978a
    APCS antibody (Cat. #AM1978a) western blot analysis in K562 cell line lysates (35μg/lane).This demonstrates the APCS antibody detected the APCS protein (arrow).
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession P02743
Other Accession NP_001630.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names 342CT9.4.7
Calculated MW 25387 Da
Additional info
Gene ID 325
Other Names Serum amyloid P-component, SAP, 95S alpha-1-glycoprotein, Serum amyloid P-component(1-203), APCS, PTX2
Target/Specificity Purified His-tagged APCS protein(Fragment) was used to produced this monoclonal antibody.
Dilution WB~~1:500~4000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAPCS Antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name APCS
Synonyms PTX2
Function Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Cellular Location Secreted.
Tissue Location Found in serum and urine.
Research Areas

BACKGROUND

The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.

REFERENCES

Song, Z., et al. Atherosclerosis 211(1):90-95(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)
Lu, J., et al. Nature 456(7224):989-992(2008)
Verwey, N.A., et al. Dement Geriatr Cogn Disord 26(6):522-527(2008)

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