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>   首页   >   产品   >   一抗   >   细胞生物学   >   DPF2 antibody (Ascites)   

DPF2 antibody (Ascites)

Mouse Monoclonal Antibody (Mab)

     
  • 1 - DPF2 antibody (Ascites) AM1897a
    All lanes : Anti-DPF2 antibody (Ascites) at 1:8000 dilution Lane 1: CHO whole cell lysate Lane 2: MDA-MB-453 whole cell lysate Lane 3: HL-60 whole cell lysate Secondary Goat Anti-mouse IgG, (H+L),Peroxidase conjugated at 1/10000 dilution. Predicted band size : 44155 Da Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q92785
Other Accession NP_006259.1
Reactivity Human, Hamster
Host Mouse
Clonality Monoclonal
Isotype IgG3,K
Clone Names 226CT14.1.1.2
Additional info
Gene ID 5977
Other Names Zinc finger protein ubi-d4, Apoptosis response zinc finger protein, BRG1-associated factor 45D, BAF45D, D4, zinc and double PHD fingers family 2, Protein requiem, DPF2, BAF45D, REQ, UBID4
Target/Specificity This DPF2 monoclonal antibody is generated from mouse immunized with DPF2 recombinant protein.
Dilution WB~~ 1:8000
Format Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDPF2 antibody (Ascites) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPF2
Synonyms BAF45D, REQ, UBID4
Function Plays an active role in transcriptional regulation by binding modified histones H3 and H4 (PubMed:28533407, PubMed:27775714). Is a negative regulator of myeloid differentiation of hematopoietic progenitor cells (PubMed:28533407). Might also have a role in the development and maturation of lymphoid cells (By similarity). Involved in the regulation of non-canonical NF-kappa-B pathway (PubMed:20460684).
Cellular Location Nucleus. Cytoplasm
Tissue Location Ubiquitous.
Research Areas

BACKGROUND

The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.

REFERENCES

Tando, T., et al. J. Biol. Chem. 285(29):21951-21960(2010)
Matsuyama, R., et al. J. Biol. Chem. 285(24):18166-18176(2010)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)

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