|Application ||WB, E|
|Other Names||Latexin, Endogenous carboxypeptidase inhibitor, ECI, Protein MUM, Tissue carboxypeptidase inhibitor, TCI, LXN|
|Target/Specificity||This LXN monoclonal antibody is generated from mouse immunized with LXN recombinant protein.|
|Format||Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LXN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.|
|Tissue Location||Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.|
Provided below are standard protocols that you may find useful for product applications.
This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Pallares, I., et al. Proc. Natl. Acad. Sci. U.S.A. 102(11):3978-3983(2005)
Liu, Q., et al. Mol. Biol. Rep. 27(4):241-246(2000)