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DRP-2 Antibody

Unpurified Mouse Monoclonal Antibody (Mab)

     
  • 1 - DRP-2 Antibody AM1131a
    All lanes : Anti-DRP-2 Antibody at 1:8000 dilution Lane 1: NIH/3T3 whole cell lysate Lane 2: Mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62, 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • 1 - DRP-2 Antibody AM1131a
    All lanes : Anti-DRP-2 Antibody at 1:128000 dilution Lane 1: human brain lysate Lane 2: mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product info
Application
  • Applications Legend:
  • E=ELISA
  • WB=Western Blotting
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin)
  • IP=Immunoprecipitation
  • IF=Immunofluorescence
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • FC=Flow Cytometry
  • DB=Dot Blot
WB, E
Primary Accession Q16555
Other Accession P47942, O08553, Q90635, O02675
Reactivity Human, Mouse
Predicted Rat, Chicken, Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG2b?
Clone Names 33CT11.7.6
Additional info
Gene ID 1808
Other Names Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2, DPYSL2, CRMP2, ULIP2
Target/Specificity This DRP-2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 463-492 amino acids from human DRP-2.
Dilution WB~~1:128000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRP-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DPYSL2
Synonyms CRMP2, ULIP2
Function Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.
Cellular Location Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Membrane. Note=Tightly but non-covalently associated with membranes
Tissue Location Ubiquitous.
Research Areas

REFERENCES

A two-stage case-control association study of the dihydropyrimidinase-like 2 gene (DPYSL2) with schizophrenia in Japanese subjects. Koide T, et al. J Hum Genet, 2010 Jul. PMID 20414250. Sex-specific proteome differences in the anterior cingulate cortex of schizophrenia. Martins-de-Souza D, et al. J Psychiatr Res, 2010 Apr 8. PMID 20381070. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614. Collapsin response mediator protein-2 regulates neurite formation by modulating tubulin GTPase activity. Chae YC, et al. Cell Signal, 2009 Dec. PMID 19666111. CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity. Arimura N, et al. J Neurochem, 2009 Oct. PMID 19659462.

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